66. Biasiotto G, Archetti S, Di Lorenzo D, Merola F, Paiardi G, Borroni B, Alberici A, Padovani A, Filosto M, Bonvicini C, Caimi L, Zanella I. A PCR-based protocol to accurately size C9orf72 intermediate-length alleles. Mol Cell Probes. 2016 Oct 17. pii: S0890 8508(16)30090-1. doi: 10.1016/j.mcp.2016.10.008


65. Giorgio Biasiotto, Isabella Zanella and Diego Di Lorenzo. Lignan as interesting food components and their health effects. International Journal of Nutritional Sciences. Vol. 1, Issue 1, 2016.


64. Isabella Zanella, Diego Di Lorenzo, Giorgio Biasiotto. Can modifier gene mutations improve the predictive value of the modified Iron Avidity Index in Type 1 Hereditary Haemochromatosis ? Liver Int. 2016, Apr 28. doi: 10.1111/liv.13153. [Epub ahead of print]


63. Giorgio Biasiotto Isabella Zanella, Alice Masserdotti, Roberta Pedrazzani, Matteo Papa, Luigi Caimi, Diego Di Lorenzo. Municipal wastewater affect adipose deposition in male mice and increase 3T3-L1 cell differentiation. Toxicol Appl Pharmacology 2016, 297:32-40. (IF: 4.163).


62. Statuto M, Galli E, Bertagna F, Migliorati E, Zanella I, Di Lorenzo D, De Agostini A, Rodella C, Apostoli P, Caimi L, Giubbini R, Biasiotto G. The strange case of the [13N]NH3: validation of the production process for human use. Nucl Med Commun. 2016, 37:412-21 (IF: 1,67).


61. Diego Di Lorenzo. Modern human genetic meets traditional medicine. New opportunities ? Health Science Journal vol.9, n°6:2. 2015.  Indexed in SCOPUS, Find Out, Medical Publishing ( Available in:


60. Isabella Zanella, Rosa Di Lorenzo, Diego Di Lorenzo. Effects of the Dietary Supplement MAK4 on Oxidative Stress Parameters: A “Three-Cases” Report. Open Access Library Journal. Dic 7. 2015. - DOI: 10.4236/oalib.1102150, PP. 1-8.


59. Giorgio Biasiotto, Diego Di Lorenzo, Silvana Archetti, Isabella Zanella. Iron and Neurodegeneration: Is Ferritinophagy the Link?. Molecular Neurobiology, October 14, 2015. 


58. Zanella I and Di Lorenzo D. Intracellular receptor regulation of adipose metabolism by the isoflavone genistein. Eur J Nutr. Jan 2015.  


57. Zanella I, Marrazzo E, Biasiotto G, Penza M, Romani A, Vignolini P, Caimi L, Di Lorenzo D.  Soy and the soy isoflavone genistein  promote adipose tissue development in male mice on a low fat diet. Eur J Nutr. 2014 Oct 24. [Epub ahead of print] PMID: 25341395. (IF:3.84).


56. Montani C, Steimberg N, Boniotti J, Biasiotto G, Zanella I, Diafera G, Biunno I, Caimi L, Mazzoleni G, Di Lorenzo D. Fibroblasts maintained in 3 dimensions show a better differentiation state and higher sensitivity to estrogens. Toxicol Appl Pharmacol. 2014 Aug 27. pii: S0041-008X(14)00313-5. doi: 10.1016/j.taap.2014.08.021.(5 years IF: 4.163).


55. Di Lorenzo D, Biasiotto G, Zanella I.  Source of iron overload in multiple sclerosis. Cell Mol Life Sci. 2014 Aug;71(16):3187-9 (IF: 5.856).


54. Biasiotto G, Penza M, Zanella I, Cadei M, Caimi L, Rossini C, Smeds A, Di Lorenzo D. Oilseeds ameliorate metabolic parameters in male mice, while contained lignans inhibit 3T3-L1 adipocyte differentiation in vitro. Eur J Nutr. 2014 Feb 25  (IF:3.84).


53. Archetti S, Martini M, Botteri E , Di Lorenzo D, Cervi E, Bonardelli S. Influence of genetic and environmental factors in peripheral arterial disease natural history. Analysis from six years follow-up. Int. J. of Appl. and Basic Med Res. (IJABMR) Jul-Dec 2012, vol.2, Issue 2.


52. Urso ED, Nascimbeni R, Pucciarelli S, Agostini M, Casella C, Moneghini D, Di Lorenzo D, Maretto I, Sullivan M, Mammi I, Viel A, Nitti D. Factors affecting the treatment of multiple colorectal adenomas. Surg Endosc. 2013 Jan;27(1):207-13.


51. Palumbo L, Cavagnini S, Notarangelo LD, Bennato V, Schumacher F, Panzali A, Di Lorenzo D, Porta F. Effetto dei polimorfismi dei geni ABCC2, MTHFR, e TYMS sulla tossicità da methotrexate in bambini oncologici. Pediatric Reports, Open Access Journal eISSN 2036-7503, 2011


50. Picco A, Archetti S, Ferrara M, Arnaldi D, Piccini A, Serrati C, Di Lorenzo D, Morbelli S, Nobili F. Seizures Can Precede Cognitive Symptoms in Late-Onset Alzheimer's Disease. J Alzheimers Dis. 2011 Aug 26.  (IF: 3.745).


49. M. Penza, M. Jeremic,  E. Marrazzo,  A. Maggi,  P. Ciana,  G. Rando,  P.G. Grigolato,  D. Di Lorenzo. The environmental chemical tributyltin chloride (TBT) shows both estrogenic and adipogenic activities in mice which might depend on the exposure dose. Toxicology and Applied Pharmacology 2011,  255 (2011) 65–75. (IF: 4.447).


48. Gervasoni A, Sandri MT, Nascimbeni R, Zorzino L, Cassatella MC, Baglioni L, Panigara S, Gervasi M, Di Lorenzo D, Parolini O. Comparison of three distinct methods for the detection of circulating tumor cells in colorectal cancer patients. Oncol Rep. 2011 Jun;25(6):1669-703. (IF: 1.835).


47. Bertanza G, Pedrazzani R, Dal Grande M, Papa M, Zambarda V, Montani C, Steimberg N, Mazzoleni G, Di Lorenzo D. Effect of biological and chemical oxidation on the removal of estrogenic compounds (NP and BPA) from wastewater: An integrated assessment procedure. Water Res. 2011 Apr;45(8):2473-84. (IF: 4.865).


46. Nascimbeni R, Pucciarelli S, Di Lorenzo D, Urso E, Casella C, Agostini M, Nitti D, Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.

Salerni B. Dis Colon Rectum. 2010 Dec;53(12):1670-5. (IF: 3.132).


45. Marchina E, Fontana MG, Speziani M, Salvi A, Ricca G, Di Lorenzo D, Gervasi M, Caimi L, Barlati S.  BRCA1 and BRCA2 genetic test in high risk patients and families: counselling and management. Oncol Rep. 2010 Dec;24(6):1661-7. (IF: 1.835).


44. Borroni B, Archetti S, Del Bo R, Papetti A, Buratti E, Bonvicini C, Agosti C, Cosseddu M, Turla M, Di Lorenzo D, Comi GP, Gennarelli M, Padovani A. TARDBP Mutations in Frontotemporal Lobar Degeneration: Frequency, Clinical Features, and Disease Course.  Rejuvenation Res. Jul 20; 2010. (IF: 3.826).


43. G. Bertanza, R. Pedrazzani, M. Papa, G. Mazzoleni, N. Steimberg, L. Caimi, C. Montani, D. Dilorenzo (2010): “Removal of BPA and NPnEOs from secondary effluents of municipal WWTPs by means of ozonation” – Ozone Science and Engineering, vol. 32, n. 3, May-June, 204-208; 2010. (IF: 1.151).


42. Pata G, Nascimbeni R, Di Lorenzo D, Gervasi M, Villanacci V, Salerni B. Hereditary multiple exostoses and juvenile colon carcinoma: A case with a common genetic background? J Surg Oncol. 2009 Nov 1;100(6):520-2. (IF: 2.1).


41. Maria Bondesson, Jill Jönsson, Ingemar Pongratz, Nicholas Olea, Jean-Pierre Cravedi, Daniel Zalko, Helen Håkansson, Krister Halldin, Diego Di Lorenzo, Christian Behl, Dieter Manthey, Patrick Balaguer, Barbara Demeneix, Jean Baptiste Fini, Vincent Laudet, Jan-Åke Gustafsson.: A CASCADE of Effects of Bisphenol A. Reproductive Toxicology, 2009, Dec;28(4):563-7. (IF: 3.226).


40. Penza M, Jeremic M, Unkila M, Caimi L, Mazzoleni G, Di Lorenzo D. Researching for alternatives to animal experimentation for hormonal compounds. Genes and Nutrition, 2009 Sep;4(3):165-72. (IF: 2.507).


39. Montani C, Penza ML, Jeremic M, Rando G, Ciana P,  Maggi A, La Sala G,  De Felici M, Di Lorenzo D. Estrogen receptor mediated transcriptional activity of genistein in the mouse testis. Trends in Comparative Endocrinology and Neurobiology: Ann N.Y. Acad. of Sciences.  1163:475-477, 2009. (IF: 3.16).


38. NascimbeniR, Villanacci V, Bassotti G, Fisogni S, Gervasi M, Rossi M, Di Lorenzo D. Colonic lymphoid follicles and NOD2/CARD15 status in Crohn’s disease. Br J Surg. 2009  96:655-62. (IF: 4.606).


37. Mazzoleni G, Di Lorenzo D and Steimberg N.  Modelling tissues in 3D: the next future of pharmaco-toxicology and food research? Genes Nutr. 2009 Dec 18, 4:13-22. (IF: 2.507).


36. Montani C., Penza M.L., Jeremic M, L., Ciana P.,  Maggi A, Di Lorenzo D.  The soy isoflavone genistein regulates estrogen receptors in several tissues of  reporter mice. Eds. A. Godoy-Matos and J. Wass. Medimond. 13th International Congress of Endocrinology. 2009, pag. 407-412.


35. Di Lorenzo D,  Gianpaolo Rando, Paolo Ciana and   Maggi A. Development and implementation of new “in vivo” systems for the   characterisation of endocrine disruptors that fulfil the 3Rs principle. Toxicol Sci. 2008 Dec;106(2):304-11. (IF: 4.652).


34. Borroni B, Archetti S, Alberici A, Agosti C, Gennarelli M, Bigni B, Bonvicini C, Ferrari M, Bellelli G, Galimberti D, Scarpini E, Di Lorenzo D, Caimi L, Caltagirone C, Di Luca M, Padovani A. Progranulin genetic variations in Frontotemporal Lobar Degeneration: evidence fro low mutation frequency in an Italian Clinical series. Neurogenetics  Apr 8. 2008. (IF: 3.354).


33. Montani C., Penza M.L., Jeremic M, L., La Sala G.,  De Felici M., Ciana P.,  Maggi A, Di Lorenzo D. Genistein is an efficient estrogen in the whole-body throughout mouse development.  Toxicol. Sci, 2008 May;103(1):57-67.


32. Penza M, Montani C, Jeremic M, Mazzoleni G, Hsiao WL, Marra M, Sharma H,  Di Lorenzo D.  MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice. BMC Complement Altern Med. 2007 Jun 8;7:19. (IF: 2.24).


31. M Penza; C Montani; A Romani; P Vignolini; P Ciana; A Maggi; B Pampaloni; L Caimi; D Di Lorenzo. Genistein accumulates in body depots and is mobilized during fasting, reaching estrogenic levels in serum that counter the hormonal actions of estradiol and organochlorines.  Toxicological   Sciences 97(2):299-307, 2007. (IF: 4.652).


30. Penza M, Montani C, Romani A, Vignolini P, Pampaloni B, Tanini A, Brandi ML, Alonso-Magdalena P, Nadal A, Ottobrini L, Parolini O, Bignotti E, Calza S, Maggi A, Grigolato PG, Di Lorenzo D. Genistein affects adipose tissue deposition in a dose-dependent and gender-specific manner. Endocrinology. 2006 Dec;147(12):5740-51 2006 (IF: 4,459).


29. Bugari G, Gambera A, Franceschini R, Busi D, Peroni M, Scagliola P, Gervasi M, Caimi L, Iacobello C, Di Lorenzo D.  Diagnosi e terapia precoce cambiano la storia naturale della malattia, bloccando l’espressione del fenotipo in pazienti con gravi alterazioni del gene della 21-alfa-idrossilasi. Ligand Assay 11:42-48,  2006.


28. A.Brena, P.Ciana, P. Sparaciari, E. Bonetti,  D.DiLorenzo and A. Maggi.. Estrogenic activities in rodent estrogen-free diet. Estrogenic activities in rodent estrogen-free diets. Endocrinology. 2005 Dec;146(12):5144-50. (IF: 4,459).


27. Mussi P, Ciana P, Raviscioni M, Villa R, Regondi S, Agradi E, Maggi A, Di Lorenzo D.  Activation of brain estrogen receptors in mice lactating from mothers exposed to DDT.  Brain Res Bull. A;65(3):241-7,2005 . (IF: 2.498).


26. R. Villa,   E. Bonetti,  M.L. Penza, C. Iacobello,  G. Bugari,  M. Bailo,b . Parolini,    P. Apostoli,   L. Caimi,  P. Ciana,  A. Maggi,  and D. Di Lorenzo.   Target-specific action of organochlorines compounds in reproductive and nonr eproductive tissues of estrogen-reporter male mice.   Toxicology Applied Pharmacology,    201, 137-148, 2004. (IF: 4,447).


25. L. Penza, E.Bonetti, R.Villa, S.Ganzerla,  R.Bergonzi, G.Biasiotto, L. Caimi, P. Apostoli, P. Ciana,  A. Maggi,  D. Di  Lorenzo. Whole body action of xenoestrogens with different chemical  structures in estrogen reporter male mice. Toxicology, , Vol 205/1-2 pp 65-73, 2004. (IF: 4,407).


24. G. Mazzoleni,   W.L.W. Hsiao,    M. Statuto,   F. Ferrari,   M. Marra,  H. Sharma  and  D. Di Lorenzo.  Anti-tumor effects of the antioxidant natural products MAK-4 and MAK–5 on cell transformation in vitro and in liver carcinogenesis in mice J. Appl. Nutr., vol. 52 (3&4), pagg. 45-63 (2002) – ISSN 0021-8960.


23. Di Lorenzo D, Villa R, Biasiotto G, Belloli S, Ruggeri G, Albertini A, Apostoli P, Raviscioni M, Ciana P, Maggi A. Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice. Endocrinology. 2002 Dec;143(12):4544-51. (IF: 4,459).


22. Usberti M, Gerardi G, Micheli A, Tira P, Bufano G, Gaggia P, Movilli E, Cancarini GC, De Marinis S, D'Avolio G, Broccoli R, Manganoni A, Albertin A, Di Lorenzo D. Effects of a vitamin E-bonded membrane and of glutathione on anemia and erythropoietin requirements in hemodialysis patients.   J Nephrol. 2002 Sep-Oct;15(5):558-64. (IF: 1,654).


21. Gerardi G, Usberti M, Martini G, Albertini A, Sugherini L, Pompella A, Di Lorenzo D. Plasma total antioxidant capacity in hemodialyzed patients and its relationships to other biomarkers of oxidative stress and lipid peroxidation. Clin Chem Lab Med. 2002 Feb;40(2):104-10. (IF: 2.15).


20. Usberti M, Gerardi G, Bufano G, Tira P, Micheli A, Albertini A, Floridi A,  Galli F,  Di Lorenzo D (shared senior authorship)

Effects of erythropoietin and vitamin E-modified membrane on plasma oxidative stress markers and anemia of hemodialyzed patients. Am J Kidney Dis. 2002 Sep;40(3):590-9. (IF: 5,434).


19. Usberti M, Gerardi GM, Gazzotti RM, Benedini S, Archetti S, Sugherini L, Valentini M, Tira P, Bufano G, Albertini A, Di Lorenzo D. Oxidative stress and cardiovascular disease in dialyzed patients. Nephron. 2002 May;91(1):25-33. (IF: 2.038).


18. Usberti M, Bufano G, Lima G, Gazzotti RM, Tira P, Gerardi G, Di Lorenzo D.Increased red blood cell survival reduces the need of erythropoietin in hemodialyzed patients treated with exogenous glutathione and vitamin E-modified membrane.

Contrib Nephrol. 1999;127:208-14. (IF: 1,49).


17. Savoldi G, Fenaroli A, Ferrari F, Rigaud G, Albertini A, Di Lorenzo D. The glucocorticoid receptor regulates the binding of C/EPBbeta on the alpha-1-acid glycoprotein promoter in vivo. DNA Cell Biol. 1997 Dec;16(12):1467-76. (IF: 2,072).


16. Garnier M, Di Lorenzo D, Albertini A, Maggi A. Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells. J Neurosci. 1997 Jun 15;17(12):4591-9. (IF: 7.27).


15. Di Lorenzo D, Ferrari F, Agrati P, de Vos H, Apostoli P, Alessio L, Albertini A, Maggi A. Manganese effects on the human neuroblastoma cell line SK-ER3. Toxicol Appl Pharmacol. 1996 Sep;140(1):51-7. (IF: 4,447).


14. Di Santo E, Sironi M, Mennini T, Zinetti M, Savoldi G, Di Lorenzo D, Ghezzi P. A glucocorticoid receptor-independent mechanism for neurosteroid inhibition of tumor necrosis factor production. Eur J Pharmacol. 1996 Mar 28;299(1-3):179-86. (IF: 2,728).


13. Magalini A, Savoldi G, Ferrari F, Garnier M, Ghezzi P, Albertini A, Di Lorenzo D.

Role of IL-1 beta and corticosteroids in the regulation of the C/EBP-alpha, beta and delta genes in vivo. Cytokine. 1995 Nov;7(8):753-8. (IF: 3,019).


12. Magalini A, Ferrari F, Savoldi G, Ingrassia R, Albertini A, Pollio G, Patrone C, Maggi A, Di Lorenzo D.  Specificity of action of a herpes virus VP16/tetracycline-dependent trans-activator in mammalian cell cultures. DNA Cell Biol. 1995 Aug;14(8):665-71. (IF: 2,072).


11. Savoldi G, Ferrari F, Ruggeri G, Sobek L, Albertini A, Di Lorenzo D.   Progesterone agonists and antagonists induce down- and up-regulation of estrogen receptors and estrogen inducible genes in human breast cancer cell lines. Int J Biol Markers. 1995 Jan-Mar;10(1):47-54. (IF: 1,479).


10. Sobek L, Di Lorenzo D, Oettel M, Kaufmann G.  Normal and stable transfected cancer cell lines: tools for a screening of progestogenic, antiprogestogenic and antiglucocorticoid substances. Methods Find Exp Clin Pharmacol. 1994 Sep;16(7):545-51. Review. (IF: 0,926).


9. Ingrassia R, Savoldi GF, Caraffini A, Tironi M, Poiesi C, Williams P, Albertini A, Di Lorenzo D. Characterization of a novel transcription complex required for glucocorticoid regulation of the rat alpha-1-acid glycoprotein gene. DNA Cell Biol. 1994 Jun;13(6):615-27. (IF: 2,072).


8. Di Lorenzo D, Gianni M, Savoldi GF, Ferrari F, Albertini A, Garattini E. Progesterone induced expression of alkaline phosphatase is associated with a secretory phenotype in T47D breast cancer cells. Biochem Biophys Res Commun. 1993 May 14;192(3):1066-72. (IF: 2,484).


7. Di Lorenzo D, Albertini A, Zava D. Progestin regulation of alkaline phosphatase in the human breast cancer cell line T47D. Cancer Res. 1991 Aug 15;51(16):4470-5. (IF: 7,856).


6. Di Lorenzo D, Ruggeri G, Iacobello C, Belloli S, Gion M, Zava DT, Ghielmi S, Albertini A.   Evaluation of a radioreceptor assay to assess exogenous estrogen activity in serum of patients with breast cancer. Int J Biol Markers. 1991 Jul-Sep;6(3):151-8. (IF: 1,479).


5. Di Lorenzo D, Williams P, Ringold G. Identification of two distinct nuclear factors with DNA binding activity within the glucocorticoid regulatory region of the rat alpha-1-acid glycoprotein promoter. Biochem Biophys Res Commun. 1991 May 15;176(3):1326-32. (IF: 2,484).


4. Klein ES,  Di Lorenzo D,  Posseckert G,  Beato M,  Ringold GM. Sequences downstream of the glucocorticoid regulatory element mediate cycloheximide inhibition of steroid induced expression from the rat alpha 1-acid glycoprotein promoter: evidence for a labile transcription factor. Mol Endocrinol. 1988 Dec;2(12):1343-51. (IF: 4,54).


3. Antonelli AR, Cappiello J, Di Lorenzo D,  Donajo CA, Nicolai P, Orlandini A.Diagnosis, staging, and treatment of juvenile nasopharyngeal angiofibroma (JNA). Laryngoscope. 1987 Nov;97(11):1319-25. (IF: 1,752).


2. Di Lorenzo D, Zaniboni A, Simoncini E, Marpicati P, Montini E, Alghisi A, Gorni F, Marini G. Estrogen and progesterone receptors in neoplastic cells of metastatic pleural effusion of breast carcinoma before and after tamoxifen therapy. Correlation with the clinical response.  Chemioterapia. 1986 Aug;5(4):232-6.


1. Zaniboni A, Di Lorenzo D, Simoncini E, Marpicati P, Gorni F, Marini G, Marinone G. Estrogen and progesterone receptor guideline for tamoxifen therapy in chronic lymphocytic leukemia: a pilot study.   Acta Haematol. 1986;75(2):92-5. (IF: 1,354).